Premium Features, Maximum Performance and Unmatched Security

Your customers need a premium, quality printer that's built to perform flawlessly—day in and day out. Give them the ZD621 desktop printer. Elevating the proven and popular GX Series printers, the ZD621 delivers an innovative new architecture to power our ever-expanding printer capabilities and software, unmatched security to safeguard sensitive data and shield from cyberattacks, plus enhanced features, communication and media-handling options that can be added at any time. The ZD621 also offers an optional full-color LCD touch display with intuitive menu and increased remote management capabilities. Together, these provide an outstanding print performance, years of optimal use, industry-leading reliability and unparalleled intelligence and security. The ZD621 provides everything needed in a printer to keep workflows fluid and business moving forward.

ZD621 printers give you premium features and performance in a compact, easy-to-use desktop printer. They're incredibly simple to install, operate, manage, maintain and secure – both onsite or remotely. Outstanding print quality paired with forward adaptability make it stand apart – for years of superior printing. And, multiple models support nearly every use case, including Healthcare and RFID.
Technology is constantly and rapidly advancing. Be ready for what’s next with the ZD621 that’s built to perform, today and tomorrow. It includes a more intuitive user interface, optional 4.3-inch full-color LCD touch display, field-upgradeable wireless kit and media handling options, as well as an innovative new architecture to power ever-expanding printer capabilities.
Security attacks are becoming increasingly sophisticated. Endpoints are becoming popular targets - including thermal printers. Proactively shield yourself from dangerous and costly security attacks on your printers. Unlike other brands, Zebra’s printers feature PrintSecure, part of Print DNA, to protect your data, secure your printer endpoints and prevent downtime.





The primary markets for the ZD621 Series are:

  • Retail
  • Healthcare
  • Transportation and Logistics
  • Manufacturing

Key applications include:


  • Return tags
  • Asset labels
  • Shelf labels
  • Price markdowns
  • Information labels
  • Pharmacy labels


  • Prescription labels
  • Lab and specimen labels
  • Patient ID wristbands
  • Asset labels
  • Blood and IV bag labels
  • Patient record labels

Transportation & Logistics:

  • Shipping and receiving labels
  • Packing slips
  • Asset labels


  • Shipping labels
  • Receiving labels
  • Agency labels
  • Packing list
  • Inventory
  • Asset tags





Innovative Features of the ZD621 Series Premium Desktop Printers

Engineered to be Easy and Secure
The ZD621 is intuitive and frustration-free, for every user. With Print DNA and setup wizards, it's easy to install and start printing quickly. Manage onsite or remotely using the robust, web-based management tool. Use Print Touch with NFC to pair and print or access how-to-videos. Plus, PrintSecure provides unmatched security for peace-of-mind protection.

Best-in-class Features
The ZD621 includes premium features, including: five status LED icons and 3-button user interface, movable sensor for greater media flexibility, media dancer for excellent print quality, fast print speed, 300 or 74 meter ribbon capacity, Ethernet, Serial, USB and USB Host, printer setup mobile app, PDF Direct, ZebraDesigner Essentials label designer, and optional 300 dpi resolution, all backed by 2-year warranty.

Flexibility to Grow
With an optional 4.3" full-color LCD touch display (standard on healthcare and RFID models) and 300 dpi resolution, the ZD621 keeps workflows moving. Field- or factory-installed options 802.11ac + Bluetooth wireless connectivity, and peeler and cutter media handling options can be added as business needs change. The battery and carrying case accessories turn the ZD621 into transportable printing solutions.

Offers Backwards Compatibility and Speaks Your Language
Customers can deploy the ZD621 into existing printer fleets with confidence. It supports both EPL and ZPL printer languages and can even emulate other printer languages using the Virtual Devices on-printer app, part of Zebra's Print DNA. And, customers can keep using their current label formats and applications—no modification needed.

RFID Without Complication
Help your customers implement RFID from the industry's broadest, field-proven portfolio. The ZD621R delivers premium printing and encoding in a compact desktop footprint. Featuring Zebra's exclusive RE40 RFID module with adaptive encoding technology, it's easy to calibrate and includes a 4.3" full-color LCD touch display standard.

Be Ready for Tomorrow's Technology
Technology is constantly and rapidly advancing. Replacing outdated equipment is costly. Be ready for what's next with the intelligent printer that's engineered to evolve. The ZD621 includes a new innovative architecture to power ever-expanding printer capabilities.



ZD621 Desktop Printer Accessories

The following accessories are available for the ZD621 printer:

  • Desktop printer battery pack and housing
  • Carrying case
  • ZKDU – Zebra keyboard display unit
  • Mounting plate
  • Enclosed power supply



Service Opportunities for the Zebra ZD421 Printers

Zebra ZD621 desktop printers come with a 2-year standard warranty. To learn more, visit the Printer Warranty Page on

Availability of Zebra's printers is key to your customers' business success. Never one-size-fits-all, choose the Zebra OneCare® maintenance plan that will best serve your customers' strategic vision, keep their printers operating at peak performance, and enable their critical business operations. Zebra OneCare plans help eliminate unexpected repair costs, maximize device uptime, and generate more revenue and margin on your printer sales. As their trusted advisor, you can add to your portfolio of services and increase your revenue and margins, while providing real value.

The recommended Zebra OneCare maintenance Plan for ZD621 Printers is Zebra OneCare Select or Zebra OneCare Essential, providing:

  • Opportunity for resellers to increase sales, margin and renewal dollars on products they sell every day, but that historically have not been sold with maintenance services. This service is available for you to sell upfront alongside all of your printers.
  • Customer to receive:
    • Zebra OneCare Essential:
      • Comprehensive repair services, including print heads
      • 3-day repair turnaround time
      • 8x5 local time technical support
      • Software updates and patches
    • Zebra OneCare Select:
      • Includes all of the features of Essential, PLUS:
        • 'Like-new' advance device replacement
        • 24x7 technical support
        • Spare pools management
        • Standard Device Commissioning preloads devices with OS, software and applications

Need Deeper Printer Visibility?

If your customers need deeper insight into their printer activity, optional cloud-based Visibility IQ™ Foresight for Link-OS Printers provides total inventory view, printer operational status (utilized, un-utilized or out of contact), smart battery data, and detailed view at the individual printer level.

Learn More



ZD621 Desktop Printer Supplies

Exceptionally Consistent Zebra Certified Supplies

The labels, tags and receipt paper used in your customer's operations provide them with critical information to their business—every year, your customers spend 3 to 10 times the cost of their Zebra printer on printing supplies. With Zebra Certified Supplies, your customers can improve operational efficiency, support the growth of their business and can even ensure brand consistency.

Using the wrong label for the application, or one that is of low quality, could lower productivity as well as customer satisfaction.

The following supplies are available for the ZD621 printer:

  • ZipShip labels, tags and receipts
  • Custom labels, tags and receipts
  • Ribbons
  • Wristbands

Consistent Processes and Materials = High Quality

  • ISO 9001:2008-certified
  • The use of consistent materials from run-to-run—we never substitute materials
  • Utilize a 23-point inspection process to ensure premium craftsmanship
  • Materials are selected to ensure we deliver consistent high-quality products

Pre-Tested Solutions Ensure Performance

  • We know thermal printers and test all materials in our printers to reduce premature printhead wear
  • Environmental testing which includes outdoor and chemical resistance
  • We offer UL and cUL certified and RoHS-compliant solutions

Learn More



ZD621 Desktop Printer Software

Print DNA Software Suite, Your Built-in Advantage
Our Print DNA suite of software gets Zebra printers up and running quickly and securely. Users can print consistently and uninterrupted with a solution that's fully integrated and interoperable—and will enable your customer's printer to evolve with their business needs.

Management Tools
Print DNA management tools make it simple to add and manage large fleets of printers from anywhere, easily.

Visibility Tools
Whether your customers have an existing MDM/EMM solution in place, or need to add visibility to their printer fleet, Zebra's got you covered.

Productivity Tools
Reach new levels of productivity with innovations that streamline tasks, optimize device performance and keep your customers ahead of the curve by solving tomorrow's problems today.

Development Tools
Print DNA allows developers to create the most functional and efficient printing solutions possible, making it easier to create unique custom apps.



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